The incidence of hyponatremia in people using MDMA
Non-randomised observational study (n=100) measuring point-of-care plasma sodium and urine drug use in MDMA users and non-users at rave parties.
Detailed Description
This study aims to determine the incidence of mild acute hyponatraemia in attendees of dance events by comparing visitors reporting recent MDMA use with non-users using a cross-sectional point-of-care approach.
Methods: participants are approached in a chill-out area from ~03:30 until the end of the event; measurements include ambient temperature, time at contact, weight/height, capillary sodium via fingerprick, urine dipstick for drug use and a short questionnaire on drug, alcohol and fluid intake. All materials and identifiers are destroyed same night; small token (ice cream) provided.
Study Arms & Interventions
MDMA users
experimentalRave visitors reporting recent MDMA use undergoing point-of-care testing and questionnaire.
Interventions
- Compoundvia Other• single measurement
Capillary point-of-care plasma sodium via fingerprick; urine dipstick for drug use; brief questionnaire on drug/alcohol/food intake and time at party.
Non-users
active comparatorRave visitors reporting no MDMA use undergoing identical testing.
Interventions
- Compoundvia Other• single measurement
Capillary point-of-care plasma sodium via fingerprick; urine dipstick for drug use; brief questionnaire.
Participants
Inclusion Criteria
- Rave visitors; at least 50 visitors who used MDMA and 50 non-users will be tested.
- Adults aged 18 years and older willing to provide anonymous participation, a fingerprick blood sample and a urine sample.
Exclusion Criteria
- Under 18 years
- Less than 2 hours at the party
- Aversion to blood (refusal of fingerprick)
Study Details
- StatusNot yet recruiting
- PhasePhase NA
- Typeobservational
- DesignNon-randomized
- Target Enrollment100 participants
- TimelineStart: 2010-04-02End: 2024-12-30
- Topic