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Perception Neuroscience is a New York–based biopharmaceutical subsidiary of atai Life Sciences developing PCN-101 (arketamine, R-ketamine) as a potentially safer, lower-dissociation alternative to racemic ketamine for treatment-resistant depression. The company completed a Phase 1 single-ascending-dose study in 58 healthy volunteers and a Phase 2a double-blind, placebo-controlled trial in TRD patients, with a collaboration with Otsuka Pharmaceutical for the Japanese market.
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