Centre hospitalier de l'Université de Montréal (CHUM)

The Centre hospitalier de l’Université de Montréal (CHUM) is one of Canada’s leading academic health centres and home to psychiatrist Dr. Nicolas Garel, co-developer of the ‘Montreal Model’—a ketamine-assisted psychotherapy protocol for severe treatment-resistant depression that integrates psychedelic-inspired non-pharmacological adjuncts with structured psychiatric care. The MUSIK trial, conducted at CHUM and published in the British Journal of Psychiatry, demonstrated sustained 8-week depression relief and established that ketamine’s mystical experiences are central to its antidepressant mechanism.