Felipe Osório
Psychiatrist and Clinical Researcher
Papers
Trials
Key Impact
Notable for clinical and translational research on ayahuasca's therapeutic potential in mood and anxiety disorders, including early randomized and neuroimaging studies and longer-term follow-ups.
Background & Research
Felipe L. Osório is a clinician-researcher who has contributed substantially to contemporary clinical research on serotonergic psychedelics, with a particular focus on ayahuasca and its effects in mood and anxiety disorders. Using a mixed-methods approach that includes randomised, placebo-controlled proof-of-concept trials, SPECT neuroimaging, and qualitative long-term follow-up, he has helped to characterise both acute antidepressant and anxiolytic effects and the persistence of therapeutic outcomes in people with recurrent depression and social anxiety. Osório is also a frequent co-author on reviews synthesising historical, pharmacological and therapeutic evidence for ayahuasca and related classic hallucinogens, advancing methodological transparency and integration of neurobiological and phenomenological data in the field.