Effects of mescaline and lysergic acid (d-LSD-25)
This early clinical study (1952) investigated the effects of mescaline (0.4 -; 0.6g) and LSD (10-120μg) in patients with schizophrenia (n=59 & 21) and found that it aggravated their symptoms and made their psychic integration even more disorganized compared to healthy individuals.
Authors
- Cattell, J. P.
- Hoch, P. H.
- Pennes, H. H.
Published
Abstract
Methods: The effects of mescaline and lysergic acid were studied in schizophrenic patients.Results: It was found that physiological changes were produced in these patients and that their mental symptomatology was markedly aggravated.Discussion: The observations made with the above-mentioned drugs on normal individuals were compared with those seen in schizophrenic patients. Mescaline and lysergic acid are drugs that disorganize the psychic integration of a person. This disorganization is much more apparent in schizophrenics than in normals. The diagnostic, prognostic, and therapeutic use of these drugs is also discussed.
Research Summary of 'Effects of mescaline and lysergic acid (d-LSD-25)'
Study Details
- Study Typeindividual
- Populationhumans
- Characteristicsopen label
- Journal
- Compounds